: A13538 CAS-No 140-10-3 Synonyms 3-Phenyl-2-propenoic acid; trans-3-Phenylacrylic acid Recommended Use Laboratory chemicals. It is found in Cinnamomum cassia. Rs 850/ Kilogram Get Latest Price. serum. Visit ChemicalBook To find more trans-Cinnamic acid(140-10-3) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes. IndiaMART > Industrial Chemicals & Supplies > Cinnamic Acid. PubChem Substance ID … Int J Cancer. Growth rates are determined by cell counting. Cells are grown for 3 days at 37°C in the presence or absence of the drug, then detached with trypsin/EDTA and counted in a Coulter counter. - Find MSDS or SDS, a COA, data sheets and more information. Briefly, 5 X104 cells are plated in each well of a 24-well plate, allowed to attach overnight, and treated with compounds (e.g., Cinnamic acid: 2.5, 5, 10, 20, 30 mM) the following day. The inhibitory concentrations causing a 50% reduction in tumor-cell proliferation (IC50) are between 1.2 to 4.5 mM. Cinnamic acid; Utilisation et sources d'émission. Freely sol in benzene, ether, acetone, glacial acetic acid, carbon disulfide, oils. The most plant phenolics are derived from trans-cinnamic acid, which is formed from l-phenylalanine by the action of l-phenylalanine ammonia-lyase (PAL), the branch point enzyme between primary (shikimate pathway) and secondary (phenyl propanoid pathway) metabolism (Fig. Service & Support. check more Cinnamic acid price, Home | Skip to page content; Skip to site menu on this page. Customer Support; Technical Service; … trans-Cinnamic acid ≥99% Synonym: trans-3-Phenylacrylic acid, Cinnamic acid CAS Number 140-10-3. Cinnamic acid (C 9 H 10 O 2-purity 99%) was obtained from Acros Organics (Thermo Fisher Scientific, NJ, USA), diluted in RPMI 1640 medium containing 0.1 g/L of L-glutamine, 2.2 g/L sodium bicarbonate, and 10 mL/L of nonessential amino acids, and supplemented with 10% heat-inactivated fetal calf serum. Cinnamic acid, ethanol and temperature interaction on coumarate decarboxylase activity and the relative expression of the putative cd gene in D. bruxellensis It is involved in the production of methyl, ethyl and benzyl esters, which is used in the perfume industry. It has a role as a plant metabolite. Cinnamic acid. It exists as both a cis and a trans isomer, although the latter is more common. Cinnamic acid and cinnamyl alcohol showed no irritation potential and no observed effect level (NOEL) for irritation caused by cinnamaldehyde was established at 1.25%. MDL number MFCD00004369. Buying Leads | Int J Cancer. Cinnamic acid CAS 140-10-3. Contact Seller Ask for best deal. 1995 Jul 28;62(3):345-50. Liu L, et al. Within 5 days of treatment with 5 mM Cinnamic acid, melanoma 1011 cells appear enlarged with a markedly increased cytoplasm-to-nuclear ratio and well organized cytoskeleton, developed long dendritic processes and became highly melanotic. Cinnamic acid; 2-Propenoic acid, 3-phenyl- (E)-; trans-3-Phenylacrylic acid; trans-beta-Carboxystyrene Chemical Name: trans-Cinnamic Acid Chemical Formula: C9-H8-O2 Contact Information: Sciencelab.com, Inc. 14025 Smith Rd. Biologically Active Compounds | Fabrication de produits organiques Hygiène et sécurité Apparence . Fabrication de produits organiques Hygiène et sécurité Apparence . LD The alkali salts are sol in water. Selling Leads | Incompatible with strong oxidizing agents. It is a member of styrenes and a member of cinnamic acids. The cell lines used, established from human malignant tumors, are A549 (lung cancer); PC3(M), Du145, and LNCaP (prostate cancer); A172, U251 (glioblastoma); and SKMEL28, A375(M), 1011 (melanoma). (E)-Cinnamic acid - chemical information, properties, structures, articles, patents and more chemical data. A. 1995 Jul 28;62(3):345-50. Get all suppliers and price by the below link: Reference only. Disclaimer, Copyright © 2018 ChemSrc All Rights Reserved. Journals | Mise à jour : 1984-01-30. At last,trans-Cinnamic acid… Il a été découvert et purifié par Péligot et Dumas en 1834. MSDS/SDS Database Search | It is a self-inhibitor produced by fungal spores to prevent germination. trans-cinnamic acid: ChEBI ID CHEBI:35697: ChEBI ASCII Name trans-cinnamic acid: Definition The E (trans) isomer of cinnamic acid: Stars This entity has been manually annotated by the ChEBI Team. Hazard Symbols: Xi - Irritant: Risk Codes: R36/37/38 - Irritating to eyes, respiratory system and skin. It serves as a precursor to the sweetener aspartame through enzyme-catalyzed amination to phenylalanine. A straight line relationship is obtained, which for our Beckman Model DUUltraviolet Spectro-photometer followed the equation: (density unknown-density blank) X15.8=mg. This factor (15.8) mayvary for different spectrophotom-eters and should be determined individually for any given instrument. Articles of Cinnamic acid are included as well. Houston, Texas 77396 US Sales: 1-800-901-7247 International Sales: 1-281-441-4400 Order Online: ScienceLab.com CHEMTREC (24HR Emergency … cinnamic acid per 100 ml. Chemsrc provides Cinnamic acid(CAS#:621-82-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Solide cristallin, jaunâtre à odeur aromatique. Cinnamic acid is an organic compound with the formula C6H5CH=CHCOOH. You can also browse global suppliers,vendor,prices,Price,manufacturers of trans-Cinnamic acid(140-10-3). Propriétés physiques . Enterprises. [1]. Stable. Classified as an unsaturated carboxylic acid, it occurs naturally in a number of plants. trans-Cinnamic acid is used in flavors, synthetic indigo and pharmaceuticals. Treatment with 5 mM Cinnamic acid results in 75-95% loss of invasiveness[1]. Synonyms: TRANS-CINNAMIC-D5 ACID. Home; Text Search; Structure Search ; About; GO. Cinnamic acids play key roles in the formation of other more complex phenolic compounds. Viability is determined by Trypan-blue exclusion assay[1]. The change in the capacity of Cinnamic acid -treated melanoma 1011, A375(M) and SKMEL28 cells to degrade and cross tissue barriers is assessed by an in vitro invasion assay using modified Boyden chambers with matrigel-coated filters. NOEL for sensitization was determined at 2.5% and 0.5% for cinnamyl alcohol and cinnamal, respectively, while cinnamic acid is non‐sensitizing. It exists as both a cis and a trans isomer, although the latter is more common. CAS Number: 621-82-9; FEMA Number: 2288; Synonyms/Related: (2E)-3-phenylprop … Mise à jour : 1986-11-10. Acide cinnamique Cinnamic acid for synthesis. It is a white crystalline compound that is slightly soluble in water, and freely soluble in many organic solvents. Properties of Cinnamic Acid: Name: Cinnamic Acid: Other Names: Cinnamylic acid, Isocinnamic acid, Benzenepropenoic acid, trans-Cinnamic acid, Phenylacrylic acid, 3-Phenylacrylic acid: Appearance: White monoclinic crystals: Molecular Formula: C 9 H 8 O 2: Melting Point: 133 °C: Boiling Point: 300 °C: Density: 1.2475 g/cm 3: Molar Mass: 148.161 g.mol –1: Solubility in Water Il est obtenu à partir de l'extrait de la cannelle, à laquelle son ester éthylique donne son odeur caractéristique, ou de certains arbustes balsamiques. EC Number 205-398-1. ACM352431482. Phenylacrylic acid; 3-Phenylacrylic acid; 3-Phenyl-2-propenoic acid, 2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%, 4-09-00-02002 (Beilstein Handbook Reference). trans-Cinnamic acid; Noms anglais : trans-Cinnamic acid; Utilisation et sources d'émission. Treatment with Cinnamic acid (CINN) of various tumor cells of epithelial and neuroectodermal origin result in dose-dependent growth inhibition following a 3-day exposure. Molecular Weight 148.16 . LD 50 (g/kg): 3.57 orally in … Articles of Cinnamic acid are included as well. The alkali salts are sol in water. cis-cinnamic acid: ChEBI ID CHEBI:35699: ChEBI ASCII Name cis-cinnamic acid: Definition The Z (cis) isomer of cinnamic acid: Stars This entity has been manually annotated by the ChEBI Team. CAS Number : 621-82-9 : Molecular Formula : C9H8O2 : Molecular weight : 148.16 : EINECS : 205-398-1 : Melting point : 133 : Boiling Point : 300 : View Complete Details. CAS 140-10-3, chemical formula C₆H₅CH=CHCOOH. Cinnamic acid: a natural product with potential use in cancer intervention. Density: 1.185g/cm 3: Melting Point: 131-136℃ Boling Point: 264.999°C at 760 mmHg: Flash Point: 189.53°C: Solubility: 0.4 g/L (20℃) Vapor Presure: 0.005mmHg at 25°C: Refractive Index: 1.616: trans-Cinnamic acid - Risk and Safety. It is a white crystalline compound that is slightly soluble in water, and freely soluble in many organic solvents. Environmental, Chemistry & Hazardous Materials News, Careers & Resources. Chemsrc provides Cinnamic acid(CAS#:621-82-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. It is a self-inhibitor produced by fungal spores to prevent germination. trans-cinnamic acid shows moderate inhibition on the rainbow trout intestinal isolates A. sobria SY-AS3 and S. baltica, SY-S145, gill isolate F. spartansii SY-FS1 and fish pathogens A. salmonicida ATCC 33658, Listonella anguillarum, SY-L24, V. crassostreae SY … Combustible. Propriétés physiques . 3.3). CINNAMIC ACID U14A832J8D Overview Structure Names 25: Classification 2: Identifiers 12: Relationships 4: Metabolites 1: Active Moiety 1: Notes 3: Audit Info References 34: History 1: … Display Name: trans-cinnamic acid EC Number: 205-398-1 EC Name: trans-cinnamic acid CAS Number: 140-10-3 Molecular formula: C9H8O2 IUPAC Name: (2E)-3-phenylprop-2-enoic acid cinnamic acid, (E)-Formula: C 9 H 8 O 2: Molar Mass: 148.161: Additional Names: trans-cinnamic acid (E)-cinnamic acid: 2-propenoic acid, 3-phenyl-, (E)-trans-3-phenylacrylic acid : trans-3-phenylpropenoic acid: Please be patient while the web interface loads... Property Availability . Get Latest Price Request a quote. Cinnamic acid, Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard, pkg of 200 mg, 1133933: Cinnamic acid, United States Pharmacopeia (USP) Reference Standard, 8.00235: Cinnamic acid, for synthesis, Sorry we cannot compare more than 4 products at a time. trans-Cinnamic acid is used in flavors, synthetic indigo and pharmaceuticals. One such malignancy that still remains a therapeutic challenge mainly due to its heterogeneity and inaccessibility to t … Chemical Database Cinnamic Acid Identifications. Identification Product Name trans-Cinnamic acid Cat No. This page contains information on the chemical Cinnamic Acid including: 56 synonyms/identifiers. It is involved in the production of methyl, ethyl and benzyl esters, which is used in the perfume industry. Molecular Formula: C 9 H 8 O 2; Molecular Weight: 148.161 g/mol; Cas Number: 140-10-3 ; EINECS Number: 205-398-1; MDL Number: MFCD00004369 ; InChIKey: WBYWAXJHAXSJNI … Service | Cinnamic acid: a natural product with potential use in cancer intervention. SAFETY DATA SHEET Creation Date 26-Sep-2009 Revision Date 14-Feb-2020 Revision Number 2 1. ChemSynthesis Chemical database. It is also showed that 20 mM Cinnamic acid is needed to cause an IC50 in FS4 cells, i.e. It serves as a precursor to the sweetener aspartame through enzyme-catalyzed amination to phenylalanine. Product Classification | Cinnamic acid. Cinnamic acid (CA) and ferulic acid (FA) are naturally occurring phenolic acids claimed to exert beneficial effects against disorders related to oxidative stress, including cancer. Solide cristallin, jaunâtre à odeur aromatique. Uses advised against Food, drug, pesticide or biocidal product use. Molecular Weight: 153.19 g/mol. 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